Val-Ala-PAB-SN38 (TFA)

MedChem Express

Val-Ala-PAB-SN38 (TFA)

999

Research Use Only

98.22

C40H42F3N5O11

825.78

Val-Ala-PAB-SN38 TFA is a drug-linker conjugate for ADC, composed of ADC linker Val-Ala-PAB (HY-125933) and SN38 (HY-13704), which is the active metabolite of the Topoisomerase I inhibitor Irinotecan (HY-16562)[1].

O=C1N2C(C(C(C2)=C(C3=C4)CC)=NC3=CC=C4O)=CC5=C1COC([C@@]5(CC)OC(OCC6=CC=C(C=C6)NC([C@H](C)NC([C@@H](N)C(C)C)=O)=O)=O)=O.OC(C(F)(F)F)=O

-20°C

41115800