Valencene [4630-07-3]

MedChem Express

Valencene [4630-07-3]

10

4630-07-3

Research Use Only

81.81

C15H24

204.35

Valencene is a sesquiterpene that can be isolated from Cyperus rotundus. Valencene possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammatory chemokines through blockade of the NF-kappaB pathway. Valencene inhibits the production and expression of proinflammatory cytokines IL-1beta and IL-6 in LPS-stimulated RAW 264.7 cells. Valencene can reduce atopic dermatitis symptoms and recover decreased expression of filaggrin in DNCB-sensitized mouse model[1][2][3].

C=C([C@@H]1CCC2=CCC[C@@H](C)[C@]2(C)C1)C

-20°C

12352200