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ProductsBack/Valproic acid

Valproic acid

HY-10585

CAS Number99-66-1

Product group Chemicals

Estimated Purity99.19

Molecular Weight144.214

Overview

Supplier
MedChem Express
Product Name
Valproic acid [99-66-1]
Delivery Days Customer
10
CAS Number
99-66-1
Certification
Research Use Only
Estimated Purity
99.19
Molecular Formula
C8H16O2
Molecular Weight
144.214
Scientific Description
Valproic acid (VPA) is an orally active HDAC inhibitor, with IC 50 in the range of 0.5 and 2 mM. Valproic acid inhibits HDAC1 ( IC 50 , 400 microM), and induces proteasomal degradation of HDAC2 . Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches [1] [2] [3] [4] [5] [6] [7] .
SMILES
CCCC(CCC)C(O)=O
Storage Instruction
RT
UNSPSC
12352200