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Valproic acid

HY-10585
MedChem Express
CAS Number99-66-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.19
Molecular Weight144.214
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Valproic acid [99-66-1]
  • Delivery Days Customer
    10
  • CAS Number
    99-66-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.19
  • Molecular Formula
    C8H16O2
  • Molecular Weight
    144.214
  • Scientific Description
    Valproic acid (VPA) is an orally active HDAC inhibitor, with IC 50 in the range of 0.5 and 2 mM. Valproic acid inhibits HDAC1 ( IC 50 , 400 microM), and induces proteasomal degradation of HDAC2 . Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches [1] [2] [3] [4] [5] [6] [7] .
  • SMILES
    CCCC(CCC)C(O)=O
  • Storage Instruction
    RT
  • UNSPSC
    12352200

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