Valproic acid-d4-1

MedChem Express

Valproic acid-d4-1 [345909-03-7]

10

345909-03-7

Research Use Only

C8H12D4O2

148.24

Valproic acid-d 4 -1 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 microM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2].

CC([2H])([2H])CC(C(O)=O)CC([2H])([2H])C

12352200