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Valproic acid (sodium) (2:1) [76584-70-8]

HY-10585B
MedChem Express
CAS Number76584-70-8
Product group Chemicals
Molecular Weight154.71
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Valproic acid (sodium) (2:1) [76584-70-8]
  • Delivery Days Customer
    10
  • CAS Number
    76584-70-8
  • Certification
    Research Use Only
  • Molecular Formula
    C8H15O2.1/2Na
  • Molecular Weight
    154.71
  • Scientific Description
    Valproic acid (VPA) sodium (2:1) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 microM), and induces proteasomal degradation of HDAC2. Valproic acid sodium (2:1) activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium (2:1) is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches[1][2][3][4][5][6][7].
  • SMILES
    CCCC(CCC)C([O-])=O.[0.5 Na+]
  • UNSPSC
    12352200