Vandetanib hydrochloride [524722-52-9]

TargetMol Chemicals

Vandetanib hydrochloride [524722-52-9]

72

524722-52-9

Research Use Only

Vandetanib hydrochloride

C22H25BrClFN4O2

511.81

Vandetanib hydrochloride (D6474 hydrochloride) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity with an IC50 of 40 nM. It also exhibits activity against VEGFR3/FLT4 tyrosine kinase activity (IC50 = 110 nM) and EGFR/HER1 (IC50 = 500 nM) [1].

3 years

Cl.COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1

-20°C

12352200