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Vandetanib (trifluoroacetate)

HY-10260A
MedChem Express
CAS Number338992-53-3
Product group Chemicals
Molecular Weight589.38
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Vandetanib (trifluoroacetate) [338992-53-3]
  • Delivery Days Customer
    10
  • CAS Number
    338992-53-3
  • Certification
    Research Use Only
  • Molecular Formula
    C24H25BrF4N4O4
  • Molecular Weight
    589.38
  • Scientific Description
    Vandetanib trifluoroacetate (D6474 trifluoroacetate) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity ( IC 50 =40 nM). Vandetanib trifluoroacetate also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 ( IC 50 =110 nM) and EGFR/HER1 ( IC 50 =500 nM) [1] .
  • SMILES
    FC1=CC(Br)=CC=C1NC2=NC=NC3=CC(OCC4CCN(CC4)C)=C(C=C23)OC.O=C(O)C(F)(F)F
  • UNSPSC
    12352200