Vardenafil hydrochloride [224785-91-5]
HY-B0442A
CAS Number224785-91-5
Product group Chemicals
Estimated Purity99.48%
Molecular Weight525.06
Overview
- SupplierMedChem Express
- Product NameVardenafil hydrochloride [224785-91-5]
- Delivery Days Customer10
- CAS Number224785-91-5
- CertificationResearch Use Only
- Estimated Purity99.48%
- Molecular FormulaC23H33ClN6O4S
- Molecular Weight525.06
- Scientific DescriptionVardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil hydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil hydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6].
- SMILESCCCC1=NC(C)=C2N1N=C(C(C=C(S(=O)(N3CCN(CC)CC3)=O)C=C4)=C4OCC)NC2=O.Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200