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Varenicline

HY-10019
MedChem Express
CAS Number249296-44-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.92
Molecular Weight211.268
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Varenicline [249296-44-4]
  • Delivery Days Customer
    10
  • CAS Number
    249296-44-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.92
  • Molecular Formula
    C13H13N3
  • Molecular Weight
    211.268
  • Scientific Description
    Varenicline (CP 526555) is an orally active partial agonist of alpha4beta2 nicotinic acetylcholine receptor (alpha4beta2 nAChR, IC 50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of alpha6beta2 nAChR and a full agonist of alpha6beta2 nAChR . Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation [1] [2] [3] [4] [5] .
  • SMILES
    C12=C(C=C3N=CC=NC3=C2)C4CC1CNC4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200