Varespladib [172732-68-2]

MedChem Express

Varespladib [172732-68-2]

10

172732-68-2

Research Use Only

98.01%

C21H20N2O5

380.39

Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively.

O=C(O)COC1=CC=CC2=C1C(C(C(N)=O)=O)=C(CC)N2CC3=CC=CC=C3

2°C to 8°C,-20°C,-80°C

12352200