(-)-Variabilin [370102-93-5]

TargetMol Chemicals

(-)-Variabilin [370102-93-5]

999

Chemical

Research Use Only

(-)-Variabilin

C17H16O5

300.31

Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; alphaIIbbeta3) and the vitronectin receptor alphavbeta3.Variabilin is also an antimicrobial furanosesterterpene. Variabilin is an inhibitor of human secretory and cytosolic phospholipase A2 (PLA2) activities that controls eicosanoid production in vitro and in vivo, inhibits neutrophil degranulation and superoxide generation in vitro and shows anti-inflammatory activity after topical or p.o. administration to mice.

3 years

COc1ccc2c(O[C@H]3c4ccc(OC)cc4OC[C@]23O)c1

-20°C

12352200