VCC234718 [1278553-16-4]
HY-118061
CAS Number1278553-16-4
Product group Chemicals
Molecular Weight387.50
Overview
- SupplierMedChem Express
- Product NameVCC234718 [1278553-16-4]
- Delivery Days Customer9
- CAS Number1278553-16-4
- CertificationResearch Use Only
- Molecular FormulaC20H25N3O3S
- Molecular Weight387.50
- Scientific DescriptionVCC234718 is a molecule with mycobacterial growth inhibitory activity, specifically targeting Mycobacterium tuberculosis (Mtb). The primary molecular target of VCC234718 is inosine monophosphate dehydrogenase (GuaB2), and it inhibits the growth of Mtb by affecting the function of this enzyme. VCC234718 inhibits GuaB2 with a K value of 100 nM and exhibits non-competitive inhibition with IMP and NAD+. VCC234718 exerts its inhibitory effect by directly interacting with IMP and binding at the NAD+ site[1].
- SMILESO=C(N1CCN(CC1)S(=O)(C2=CC=CC3=C2C=CN=C3)=O)C4CCCCC4
- UNSPSC12352200