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VDAC2 antibody [C2C3], C-term

GTX104745
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetVDAC2
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Overview

  • Supplier
    GeneTex
  • Product Name
    VDAC2 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.65 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7417
  • Target name
    VDAC2
  • Target description
    voltage dependent anion channel 2
  • Target synonyms
    POR, non-selective voltage-gated ion channel VDAC2, epididymis secretory sperm binding protein, outer mitochondrial membrane protein porin 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP45880
  • Protein Name
    Non-selective voltage-gated ion channel VDAC2
  • Scientific Description
    This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lin N, van Zomeren K, van Veen T, et al. Quantum Sensing of Free Radicals in Primary Human Granulosa Cells with Nanoscale Resolution. ACS Cent Sci. 2023,9(9):1784-1798. doi: 10.1021/acscentsci.3c00747
    Read this paper
  • She H, Tan L, Du Y, et al. VDAC2 malonylation participates in sepsis-induced myocardial dysfunction via mitochondrial-related ferroptosis. Int J Biol Sci. 2023,19(10):3143-3158. doi: 10.7150/ijbs.84613
    Read this paper
  • Sharmin R, Nusantara AC, Nie L, et al. Intracellular Quantum Sensing of Free-Radical Generation Induced by Acetaminophen (APAP) in the Cytosol, in Mitochondria and the Nucleus of Macrophages. ACS Sens. 2022,7(11):3326-3334. doi: 10.1021/acssensors.2c01272
    Read this paper
  • Lee CW, Huang CC, Chi MC, et al. Naringenin Induces ROS-Mediated ER Stress, Autophagy, and Apoptosis in Human Osteosarcoma Cell Lines. Molecules. 2022,27(2). doi: 10.3390/molecules27020373
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  • Nie L, Nusantara AC, Damle VG, et al. Quantum monitoring of cellular metabolic activities in single mitochondria. Sci Adv. 2021,7(21). doi: 10.1126/sciadv.abf0573
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  • Chen CY, Lee DS, Choong OK, et al. Cardiac-specific microRNA-125b deficiency induces perinatal death and cardiac hypertrophy. Sci Rep. 2021,11(1):2377. doi: 10.1038/s41598-021-81700-y
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  • Lo YW, Lin ST, Chang SJ, et al. Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer. J Cell Mol Med. 2015,19(4):744-59. doi: 10.1111/jcmm.12388
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  • Cho CK, Smith CR, Diamandis EP. Amniotic fluid proteome analysis from Down syndrome pregnancies for biomarker discovery. J Proteome Res. 2010,9(7):3574-82. doi: 10.1021/pr100088k
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