ProductsBack/VEGFA antibody [4E3]

IHC-P analysis of human breast adenocarcinoma tissue using GTX83426 VEGFA antibody [4E3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.

VEGFA antibody [4E3]

GTX83426

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman

TargetVEGFA

Overview

Supplier
GeneTex
Product Name
VEGFA antibody [4E3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:2000. ICC/IF: 1:100. IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Monoclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID7422
Target name
VEGFA
Target description
vascular endothelial growth factor A
Target synonyms
L-VEGF, MVCD1, VEGF, VPF, vascular endothelial growth factor A, long form, vascular endothelial growth factor A121, vascular endothelial growth factor A165, vascular permeability factor
Host
Mouse
Isotype
IgG1
Protein IDP15692
Protein Name
Vascular endothelial growth factor A, long form
Scientific Description
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Quintero Sierra LA, Busato A, Zingaretti N, et al. Tissue-Material Integration and Biostimulation Study of Collagen Acellular Matrices. Tissue Eng Regen Med. 2022,19(3):477-490. doi: 10.1007/s13770-021-00420-6
Read this paper
Merigo F, Brandolese A, Facchin S, et al. Immunolocalization of leptin and leptin receptor in colorectal mucosa of ulcerative colitis, Crohn's disease and control subjects with no inflammatory bowel disease. Cell Tissue Res. 2021,383(3):1103-1122. doi: 10.1007/s00441-020-03297-4
Read this paper
De Francesco F, Busato A, Mannucci S, et al. Artificial dermal substitutes for tissue regeneration: comparison of the clinical outcomes and histological findings of two templates. J Int Med Res. 2020,48(8):300060520945508. doi: 10.1177/0300060520945508
Read this paper

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VEGFA antibody [4E3]

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Overview

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