WB analysis of PAE cells transfected with a chimeric receptor and stimulated with CSF (Lane 1-4) or from NIH3T3 cells transfected with human VEGFR2 left unstimulated (Lane 5) or stimulated with VEGF (Lane 6) using GTX25472 VEGF Receptor 2 (phospho Tyr1054) antibody.
WB analysis of PAE cells transfected with a chimeric receptor and stimulated with CSF (Lane 1-4) or from NIH3T3 cells transfected with human VEGFR2 left unstimulated (Lane 5) or stimulated with VEGF (Lane 6) using GTX25472 VEGF Receptor 2 (phospho Tyr1054) antibody.
VEGF Receptor 2 (phospho Tyr1054) antibody
GTX25472
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetKdr
Overview
- SupplierGeneTex
- Product NameVEGF Receptor 2 (phospho Tyr1054) antibody - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 0.35-1.0 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID16542
- Target nameKdr
- Target descriptionkinase insert domain protein receptor
- Target synonyms6130401C07; fetal liver kinase 1; Flk; Flk-; Flk1; Flk-1; kinase NYK; Krd-1; Ly73; orv; protein-tyrosine kinase receptor flk-1; soluble vascular endothelial growth factor receptor 2; sVEGFR-2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor-3; VEGF; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionVascular endothelial growth factor receptor 2 (VEGFR 2, also known as KDR / FLK 1) is a 200 kDa member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGFR 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2- and phosphotyrosine binding containing signaling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGFR 2 and its intrinsic tyrosine kinase activity.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203