VEGFC antibody
GTX113574
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Rat
TargetVEGFC
Overview
- SupplierGeneTex
- Product NameVEGFC antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID7424
- Target nameVEGFC
- Target descriptionvascular endothelial growth factor C
- Target synonymsFLT4 ligand DHM; Flt4-L; LMPH1D; LMPHM4; vascular endothelial growth factor C; vascular endothelial growth factor-related protein; VRP
- HostRabbit
- IsotypeIgG
- Protein IDP49767
- Protein NameVascular endothelial growth factor C
- Scientific DescriptionThe protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq]
- ReactivityBovine, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The significance of SMARCB1 in the pathogenesis of renal cell carcinoma with rhabdoid features. Wang YW et al., 2021 Oct, Transl OncolRead more
- Increased secretion of VEGF-C from SiO2-induced pulmonary macrophages promotes lymphangiogenesis through the Src/eNOS pathway in silicosis. Zhang J et al., 2021 Apr 29, Ecotoxicol Environ SafRead more
- DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination. Wang CA et al., 2020, J Extracell VesiclesRead more
- Temporal expression and localization of vascular endothelial growth factor family members in the bovine uterus during peri-implantation period. Hayashi KG et al., 2019 Jul 15, TheriogenologyRead more
- High Glucose Induces VEGF-C Expression via the LPA1/3-Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells. Huang YL et al., 2018, Cell Physiol BiochemRead more
- LPA1/3 signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer. Lin YC et al., 2018 Oct, Biochim Biophys Acta Mol Cell Biol LipidsRead more
- Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells. Huang YH et al., 2016, PLoS OneRead more