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VEGFC antibody

Name: VEGFC antibody
SKU: GTX113574_G10
Availability: BackOrder

GTX113574

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetVEGFC

Overview

Supplier
GeneTex
Product Name
VEGFC antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.3 mg/ml
Conjugate
Unconjugated
Gene ID7424
Target name
VEGFC
Target description
vascular endothelial growth factor C
Target synonyms
FLT4 ligand DHM; Flt4-L; LMPH1D; LMPHM4; vascular endothelial growth factor C; vascular endothelial growth factor-related protein; VRP
Host
Rabbit
Isotype
IgG
Protein IDP49767
Protein Name
Vascular endothelial growth factor C
Scientific Description
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

The significance of SMARCB1 in the pathogenesis of renal cell carcinoma with rhabdoid features. Wang YW et al., 2021 Oct, Transl Oncol
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Increased secretion of VEGF-C from SiO2-induced pulmonary macrophages promotes lymphangiogenesis through the Src/eNOS pathway in silicosis. Zhang J et al., 2021 Apr 29, Ecotoxicol Environ Saf
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DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination. Wang CA et al., 2020, J Extracell Vesicles
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Temporal expression and localization of vascular endothelial growth factor family members in the bovine uterus during peri-implantation period. Hayashi KG et al., 2019 Jul 15, Theriogenology
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High Glucose Induces VEGF-C Expression via the LPA1/3-Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells. Huang YL et al., 2018, Cell Physiol Biochem
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LPA1/3 signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer. Lin YC et al., 2018 Oct, Biochim Biophys Acta Mol Cell Biol Lipids
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Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells. Huang YH et al., 2016, PLoS One
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