VEGFC antibody
GTX113574
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetVEGFC
Overview
- SupplierGeneTex
- Product NameVEGFC antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID7424
- Target nameVEGFC
- Target descriptionvascular endothelial growth factor C
- Target synonymsFlt4-L, LMPH1D, LMPHM4, VRP, vascular endothelial growth factor C, FLT4 ligand DHM, vascular endothelial growth factor-related protein
- HostRabbit
- IsotypeIgG
- Protein IDP49767
- Protein NameVascular endothelial growth factor C
- Scientific DescriptionThe protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wang YW, Song HL, Chiang CY, et al. The significance of SMARCB1 in the pathogenesis of renal cell carcinoma with rhabdoid features. Transl Oncol. 2021,14(10):101175. doi: 10.1016/j.tranon.2021.101175Read this paper
- Zhang J, Cui J, Li X, et al. Increased secretion of VEGF-C from SiO(2)-induced pulmonary macrophages promotes lymphangiogenesis through the Src/eNOS pathway in silicosis. Ecotoxicol Environ Saf. 2021,218:112257. doi: 10.1016/j.ecoenv.2021.112257Read this paper
- Wang CA, Chang IH, Hou PC, et al. DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination. J Extracell Vesicles. 2020,9(1):1746529. doi: 10.1080/20013078.2020.1746529Read this paper
- Hayashi KG, Hosoe M, Fujii S, et al. Temporal expression and localization of vascular endothelial growth factor family members in the bovine uterus during peri-implantation period. Theriogenology. 2019,133:56-64. doi: 10.1016/j.theriogenology.2019.04.021Read this paper
- Huang YL, Lin YC, Lin CC, et al. High Glucose Induces VEGF-C Expression via the LPA1/3-Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells. Cell Physiol Biochem. 2018,50(2):597-611. doi: 10.1159/000494177Read this paper
- Lin YC, Chen CC, Chen WM, et al. LPA(1/3) signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer. Biochim Biophys Acta Mol Cell Biol Lipids. 2018,1863(10):1305-1315. doi: 10.1016/j.bbalip.2018.07.005Read this paper
- Huang YH, Yang HY, Huang SW, et al. Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells. PLoS One. 2016,11(7):e0158839. doi: 10.1371/journal.pone.0158839Read this paper
Datasheet
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