VEGFR-2/AKT-IN-2
HY-169431
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameVEGFR-2/AKT-IN-2
- Delivery Days Customer5
- CertificationResearch Use Only
- Scientific DescriptionVEGFR-2/AKT-IN-2 (Compound 5) is a VEGFR-2/AKT inhibitor (IC50: 0.061 microM for VEGFRin HepG2 cell). VEGFR-2/AKT-IN-2 reduces total and phosphorylated AKT as well as up-regulates BAX and Caspase-3 and down-regulates Bcl-2 in cells, thereby promoting Apoptosis. VEGFR-2/AKT-IN-2 causes cell cycle arrest in S phase. VEGFR-2/AKT-IN-2 inhibits the growth of human liver tumor cells[1].
- UNSPSC12352200