VEGFR-2/BRAF-IN-1
HY-146491
Molecular Weight642.5
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameVEGFR-2/BRAF-IN-1
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC26H20Cl2F3N5O3S2
- Molecular Weight642.5
- Scientific DescriptionVEGFR-2/BRAF-IN-1 (Compound 4b) is a dual VEGFR-2 and BRAF kinases inhibitor with IC50 values of 0.049, 0.063 and 0.005 microM against VEGFR-2, BRAFV600E and BRAFWT, respectively. VEGFR-2/BRAF-IN-1 induces apoptosis and arrests the cell cycle mainly in the G1/S phase.
- SMILESO=C(NNC(NC1=CC(C(F)(F)F)=C(C=C1)Cl)=O)CSC2=NC3=C(C4=C(S3)CCCC4)C(N2C5=CC=C(C=C5)Cl)=O
- Storage InstructionSee Manual
- UNSPSC12352200