VEGFR-2/BRAF-IN-2
HY-146492
Molecular Weight608.05
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameVEGFR-2/BRAF-IN-2
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC26H21ClF3N5O3S2
- Molecular Weight608.05
- Scientific DescriptionVEGFR-2/BRAF-IN-2 (Compound 4a) is a dual VEGFR-2 and BRAF kinases inhibitor with IC50 values of 0.111, 0.089 and 0.071 microM against VEGFR-2, BRAFV600E and BRAFWT, respectively. VEGFR-2/BRAF-IN-2 induces apoptosis and arrests the cell cycle mainly in the G1 phase.
- SMILESFC(F)(F)C1=CC=CC(NC(NNC(CSC2=NC3=C(C4=C(S3)CCCC4)C(N2C5=CC=C(C=C5)Cl)=O)=O)=O)=C1
- Storage InstructionSee Manual
- UNSPSC12352200