VEGFR-2/DHFR-IN-1

TargetMol Chemicals

VEGFR-2/DHFR-IN-1

107

Chemical

VEGFR-2/DHFR-IN-1

C20H18ClNO4

371.81

VEGFR-2/DHFR-IN-1 (compound 8b) is an inhibitor of VEGFR-2 and DHFR with IC 50 s of 0.384 and 7.881 uM, respectively. VEGFR-2/DHFR-IN-1 shows good antibacterial activities against Escherichia coli, Streptococcus faecalis, Salmonella enterica, MSSA and MRSA with MIC values of 16, 16, 16, 8, and 16 ug/mL, respectively. VEGFR-2/DHFR-IN-1 exhibits good cytotoxic activities against C26, HepG2, and MCF7 cancer cell lines with IC 50 values of 2.97-7.12 uM. VEGFR-2/DHFR-IN-1 can be used for the research of cancer [1].

3 years

#Reference to error in column [smiles]

-20°

12352200