VEGFR2/HDAC1-IN-1

MedChem Express

VEGFR2/HDAC1-IN-1 [3024922-89-9]

14

Research Use Only

C27H30N4O7

522.55

VEGFR2/HDAC1-IN-1 (compound 13) is a potent VEGFR-2/HDAC dual inhibitor, with IC50s of 57.83 nM and 9.82 nM, respectively. VEGFR2/HDAC1-IN-1 arrests the cell cycle at the S and G2 phases, and induces apoptosis in HeLa cells. VEGFR2/HDAC1-IN-1 exhibits anti-angiogenic effect[1].

CC1=C(C(NC)=O)C(C=C2)=C(O1)C=C2OC3=NC=NC4=CC(OC)=C(OCCCCCCC(NO)=O)C=C43

12131703