Vemurafenib-d5 [1365986-90-8]

MedChem Express

Vemurafenib-d5 [1365986-90-8]

10

1365986-90-8

Research Use Only

C23H13D5ClF2N3O3S

494.95

Vemurafenib-d5 is the deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].

C(=O)(C=1C=2C(NC1)=NC=C(C2)C3=CC=C(Cl)C=C3)C4=C(F)C(NS(CC(C([2H])([2H])[2H])([2H])[2H])(=O)=O)=CC=C4F

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