Vemurafenib-d7

MedChem Express

Vemurafenib-d7

10

Research Use Only

C23H11D7ClF2N3O3S

496.97

Vemurafenib-d7 is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].

O=C(C1=C(C(NS(C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])(=O)=O)=CC=C1F)F)C2=CNC3=NC=C(C4=CC=C(C=C4)Cl)C=C23

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