Venetoclax [1257044-40-8]

TargetMol Chemicals

Venetoclax [1257044-40-8]

4

1257044-40-8

Chemical

Research Use Only

Venetoclax

99.96%

C45H50ClN7O7S

868.44

Venetoclax (ABT-199) is a Bcl-2 inhibitor (Ki<0.01 nM) with potent, selective, and orally active properties. Venetoclax has a 3-order-of-magnitude lower affinity for Bcl-xL and Bcl-W (Kis=48/245 nM). Venetoclax induces autophagy and apoptosis.

3 years

O=C(C1=CC=C(N2CCN(CC2)CC3=C(CC(C)(CC3)C)C4=CC=C(Cl)C=C4)C=C1OC5=CC6=C(NC=C6)N=C5)NS(=O)(C7=CC=C(C([N+]([O-])=O)=C7)NCC8CCOCC8)=O

-20°C

12352200