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Vernakalant (Hydrochloride) [748810-28-8]

HY-14183
MedChem Express
CAS Number748810-28-8
Product group Chemicals
Estimated Purity99.33
Molecular Weight385.93
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Vernakalant (Hydrochloride) [748810-28-8]
  • Delivery Days Customer
    10
  • CAS Number
    748810-28-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.33
  • Molecular Formula
    C20H32ClNO4
  • Molecular Weight
    385.93
  • Scientific Description
    Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker. IC50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35+/-0.93 microM, 0.61+/-0.03 microM, and 1.63+/-0.09 microM for Kv1.5 channelwt, Kv1.5 channelI508F, Kv1.5 channelT479A, respectively.
  • SMILES
    COC1=C(OC)C=C(CCO[C@H]2[C@H](N3CC[C@@H](O)C3)CCCC2)C=C1.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200