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Chemical Structure
Chemical Structure
Chemical Structure

Verruculogen [12771-72-1]

BVT-0443
BioViotica
CAS Number12771-72-1
Product group Chemicals
Estimated Purity>98%
Molecular Weight511.6
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Overview

  • Supplier
    BioViotica
  • Product Name
    Verruculogen [12771-72-1]
  • Delivery Days Customer
    10
  • CAS Number
    12771-72-1
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Danger,Excepted quantity
  • Molecular Formula
    C27H33N3O7
  • Molecular Weight
    511.6
  • Scientific Description
    Chemical. CAS: 12771-72-1. Formula: C27H33N3O7. MW: 511.6. Isolated from Aspergillus fumigatus. Fumitremorgin-type alkaloid. Tremorgenic neurotoxic mycotoxin. Selective blocker of KCa1.1 (high-conductance Ca2+-activated K+; BK; maxi-K) channels. Decreases GABA levels in CNS. Increases spontaneous glutamate and aspartate release. At toxic doses, increases the number and decreases the affinity of DHP receptors in rat cortex. Cell cycle inhibitor at the M phase. Inhibits calmodulin and PKC activity. Has apoptotic effects on human T lymphocytes. Stimulates the growth of seedling roots of buckwheat. - Fumitremorgin-type alkaloid. Tremorgenic neurotoxic mycotoxin. Selective blocker of KCa1.1 (high-conductance Ca2+-activated K+; BK; maxi-K) channels. Decreases GABA levels in CNS. Increases spontaneous glutamate and aspartate release. At toxic doses, increases the number and decreases the affinity of DHP receptors in rat cortex. Cell cycle inhibitor at the M phase. Inhibits calmodulin and PKC activity. Has apoptotic effects on human T lymphocytes. Stimulates the growth of seedling roots of buckwheat.
  • SMILES
    O=C(N[C@H](CCCC)C(O[Na])=O)[C@@H](C1=CN(C(OC)=O)C2=C1C=CC=C2)NC([C@H](CC(C)(C)C)NC(N3[C@H](C)CCC[C@@H]3C)=O)=OO=C1N2[C@](CCC2)([H])C(N([C@@]1(O)[C@H]3O)[C@@]4([H])CC(C)(C)OO[C@@](/C=C(C)\C)([H])N5C4=C3C6=C5C=C(OC)C=C6)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UN Number
    UN 2811
  • UNSPSC
    12352200

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