Verubecestat

MedChem Express

Verubecestat [1286770-55-5]

10

1286770-55-5

Research Use Only

99.56

C17H17F2N5O3S

409.41

Verubecestat (MK-8931) is an orally active, high-affinity BACE1 and BACE2 inhibitor with K i values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Abeta40 and has the potential for Alzheimers Disease [1] [2] .

O=C(C1=NC=C(F)C=C1)NC2=CC=C(F)C([C@@](C3)(C)N=C(N)N(C)S3(=O)=O)=C2

-20°C,2°C to 8°C

12352200