VF-57a

MedChem Express

VF-57a

5

Research Use Only

C15H13ClF3NOS

347.78

VF-57a (Compound 23) is an Influenza A virus (IAV) fusion inhibitor. VF-57 has potent antiviral activities against authentic A/H1N1 virus with EC50s of 0.92 and 0.31 microM for the A/H1N1 PR8 and A/H1N1 Virg09 strains, respectively. VF-57 significantly inhibits HA-mediated cell entry of A/H1N1- and A/H5N1-pseudoviruses, prevents the HA refolding at pH 5.2. VF-57a can be used for IAV infections research[1].

O=C(NCC1=C(C)SC(C)=C1)C2=CC(C(F)(F)F)=CC(Cl)=C2

12352200