VH-298
HY-100947
CAS Number2097381-85-4
Product group Chemicals
Estimated Purity99.83
Molecular Weight523.65
Overview
- SupplierMedChem Express
- Product NameVH-298 [2097381-85-4]
- Delivery Days Customer10
- CAS Number2097381-85-4
- Estimated Purity99.83
- Molecular FormulaC27H33N5O4S
- Molecular Weight523.65
- Scientific DescriptionVH-298 is a highly potent inhibitor of the VHL:HIF-alpha interaction with a K d value of 80 to 90 nM. VH-298 leads to HIF-alpha accumulation inside HeLa cells. VH-298 is an E3 ligase Ligand, and can be used for synthesis of PROTACs [1] .
- SMILESO=C([C@H]1N(C([C@H](C(C)(C)C)NC(C2(CC2)C#N)=O)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200