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VH-298

HY-100947
MedChem Express
CAS Number2097381-85-4
Product group Chemicals
Estimated Purity99.83
Molecular Weight523.65
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VH-298 [2097381-85-4]
  • Delivery Days Customer
    10
  • CAS Number
    2097381-85-4
  • Estimated Purity
    99.83
  • Molecular Formula
    C27H33N5O4S
  • Molecular Weight
    523.65
  • Scientific Description
    VH-298 is a highly potent inhibitor of the VHL:HIF-alpha interaction with a K d value of 80 to 90 nM. VH-298 leads to HIF-alpha accumulation inside HeLa cells. VH-298 is an E3 ligase Ligand, and can be used for synthesis of PROTACs [1] .
  • SMILES
    O=C([C@H]1N(C([C@H](C(C)(C)C)NC(C2(CC2)C#N)=O)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200