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VH032 thiol

VH032 thiol

T18600
TargetMol Chemicals
CAS Number2098836-54-3
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Product group Chemicals
Molecular Weight490.64
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    VH032 thiol
  • Delivery Days Customer
    1001
  • CAS Number
    2098836-54-3
  • Category Supplier
    Chemical
  • Chemical Name
    VH032 thiol
  • Molecular Formula
    C23H30N4O4S2
  • Molecular Weight
    490.64
  • Scientific Description
    VH032 thiol (VHL ligand 6) is a VHL ligand that interacts with pan-BET inhibitor JQ1 through a linker to create a PROTAC[1] compound.
  • Shelf life instruction
    3 years
  • SMILES
    C([C@@H](NC(C)=O)[C@](C)(C)S)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C=3SC=NC3C)=O)C[C@@H](O)C1
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.
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