VHL, Human (His)
HY-P76124
Protein IDP40337
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameVHL, Human (His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity90.00
- Gene ID7428
- Target nameVHL
- Target descriptionvon Hippel-Lindau tumor suppressor
- Target synonymsHRCA1, RCA1, VHL1, pVHL, von Hippel-Lindau disease tumor suppressor, elongin binding protein, protein G7, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
- Protein IDP40337
- Protein Namevon Hippel-Lindau disease tumor suppressor
- Scientific DescriptionVHL protein is an important component of the von Hippel-Lindau ubiquitination complex and plays a key role in ubiquitination and proteasomal degradation. As a target recruitment subunit in the E3 ubiquitin ligase complex, VHL specifically recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions and regulates cellular responses to oxygen levels. VHL Protein, Human (His) is the recombinant human-derived VHL protein, expressed by E. coli , with N-6*His labeled tag.
- Storage Instruction-20°C
- UNSPSC41116100

