Bio-Connect

VHL, Human (His)

HY-P76124
MedChem Express
Protein IDP40337
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VHL, Human (His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    90.00
  • Gene ID7428
  • Target name
    VHL
  • Target description
    von Hippel-Lindau tumor suppressor
  • Target synonyms
    HRCA1, RCA1, VHL1, pVHL, von Hippel-Lindau disease tumor suppressor, elongin binding protein, protein G7, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
  • Protein IDP40337
  • Protein Name
    von Hippel-Lindau disease tumor suppressor
  • Scientific Description
    VHL protein is an important component of the von Hippel-Lindau ubiquitination complex and plays a key role in ubiquitination and proteasomal degradation. As a target recruitment subunit in the E3 ubiquitin ligase complex, VHL specifically recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions and regulates cellular responses to oxygen levels. VHL Protein, Human (His) is the recombinant human-derived VHL protein, expressed by E. coli , with N-6*His labeled tag.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100