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ProductsBack/Vif-ElonginC interaction inhibitor 1 [374679-27-3]

Vif-ElonginC interaction inhibitor 1 [374679-27-3]

HY-120157
MedChem Express
CAS Number374679-27-3
Product group Chemicals
Molecular Weight447.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Vif-ElonginC interaction inhibitor 1 [374679-27-3]
  • Delivery Days Customer
    14
  • CAS Number
    374679-27-3
  • Certification
    Research Use Only
  • Molecular Formula
    C29H21NO4
  • Molecular Weight
    447.48
  • Scientific Description
    Vif-ElonginC interaction inhibitor 1 (compound VEC-5) is a potent Vif inhibitor. Vif-ElonginC interaction inhibitor 1 can restrict HIV-1 in Vif-nonpermissive cells. Vif-ElonginC interaction inhibitor 1 can protect A3G, APOBEC3C (A3C), and APOBEC3F (A3F) from Vif-mediated degradation and drastically inhibit Vif function through blocking the interaction between Vif and ElonginC. Vif-ElonginC interaction inhibitor 1 enhances A3G incorporation into HIV-1 virions to reduce viral infectivity[1].
  • SMILES
    O=C(OCC)C1=C2C=C(C=CN2C(C(C3=CC=C4C=CC=CC4=C3)=O)=C1)C(C5=CC=CC=C5)=O
  • UNSPSC
    12352200

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