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ProductsBack/Viridicatumtoxin [39277-41-3]
Chemical Structure
Chemical Structure
Chemical Structure

Viridicatumtoxin [39277-41-3]

Research Use Only
AG-CN2-0172
AdipoGen Life Sciences
CAS Number39277-41-3
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight565.6
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Viridicatumtoxin
  • Delivery Days Customer
    10
  • ADR Class
    6.1
  • CAS Number
    39277-41-3
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C30H31NO10
  • Molecular Weight
    565.6
  • Scientific Description
    Chemical. CAS: 39277-41-3. Formula: C30H31NO10. MW: 565.6. Isolated from Penicillium brasilianum. Mycotoxin. Tetracycline antibiotic. Potent antibacterial agent with activity against several strains of Staphylococcus aureus, including Methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA). Inhibits bacterial undecaprenyl pyrophosphate (UPP) synthase activity. Modest antitumor agent against selected cancer cell lines (IC50~1microM). - Mycotoxin. Tetracycline antibiotic. Potent antibacterial agent with activity against several strains of Staphylococcus aureus, including Methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA). Inhibits bacterial undecaprenyl pyrophosphate (UPP) synthase activity. Modest antitumor agent against selected cancer cell lines (IC50~1microM).
  • SMILES
    OC(C[C@]1(O)[C@@H](O)C2=C(C[C@]34C(C)=CCCC4(C)C)C(C3=C(OC)C=C5O)=C5C(O)=C2C6=O)=C(C(N)=O)C([C@]16O)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UN Number
    2811
  • UNSPSC
    12352200

References

  • Viridicatumtoxin, a new mycotoxin from Penicillium viridicatum Westling: R.D. Hutchison, et al.; Toxicol. Appl. Pharmacol. 24, 507 (1973)
  • Microbial transformations of natural antitumor agents. 20. Glucosylation of Viridicatumtoxin: M.S. Raju, et al.; J. Nat. Prod. 45, 321 (1982)
  • Viridicatumtoxin mycotoxicosis in mice and rats: A.M. Bendele, et al.; Toxicol. Lett. 22, 287 (1984)
  • Viridicatumtoxin B, a new anti-MRSA agent from Penicillium sp. FR11: C.J. Zheng, et al.; J. Antibiot. 61, 633 (2008)
  • Viridicatumtoxins: Expanding on a Rare Tetracycline Antibiotic Scaffold: T. Shang, et al.; J. Org. Chem. 80, 12501 (2015)
  • Inhibition of bacterial undecaprenyl pyrophosphate synthase by small fungal molecules: J. Inokoshi, et al.; J. Antibiot. 69,798 (2016)