Vismodegib

MedChem Express

Vismodegib [879085-55-9]

10

879085-55-9

Research Use Only

99.97

C19H14Cl2N2O3S

421.29706

Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC 50 of 3 nM. Vismodegib also inhibits P-gp , ABCG2 with IC 50 values of 3.0 microM and 1.4 microM, respectively [1] [2] .

O=C(C1=CC=C(C=C1Cl)S(=O)(C)=O)NC2=CC=C(C(C3=NC=CC=C3)=C2)Cl

-20°C,2°C to 8°C

12352200