Vistusertib (AZD2014)

Selleck Chemicals

Vistusertib (AZD2014) [1009298-59-2]

9

Research Use Only

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Vistusertib (AZD2014) is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay; highly selective against multiple PI3K isoforms (alpha/beta/gamma/delta). AZD2014 showed no or weak binding to the majority of kinases when tested at 1 microM. AZD2014 induces proliferation suppression, apoptosis, cell cycle arrest, and autophagy in HCC cells with antitumor activity.

-80°C

51202000