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Vitronectin antibody

GTX103475
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetVTN
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Overview

  • Supplier
    GeneTex
  • Product Name
    Vitronectin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.34 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7448
  • Target name
    VTN
  • Target description
    vitronectin
  • Target synonyms
    V75, VN, VNT, vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP04004
  • Protein Name
    Vitronectin
  • Scientific Description
    The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Fox CR, Parks GD. Complement Inhibitors Vitronectin and Clusterin Are Recruited from Human Serum to the Surface of Coronavirus OC43-Infected Lung Cells through Antibody-Dependent Mechanisms. Viruses. 2021,14(1). doi: 10.3390/v14010029
    Read this paper
  • Sato K, Kumagai Y, Sekizuka T, et al. Vitronectin binding protein, BOM1093, confers serum resistance on Borrelia miyamotoi. Sci Rep. 2021,11(1):5462. doi: 10.1038/s41598-021-85069-w
    Read this paper
  • Yang F, Wei Y, Han D, et al. Interaction with CD68 and Regulation of GAS6 Expression by Endosialin in Fibroblasts Drives Recruitment and Polarization of Macrophages in Hepatocellular Carcinoma. Cancer Res. 2020,80(18):3892-3905. doi: 10.1158/0008-5472.CAN-19-2691
    Read this paper
  • Seto S, Morimoto K, Yoshida T, et al. Proteomic Profiling Reveals the Architecture of Granulomatous Lesions Caused by Tuberculosis and Mycobacterium avium Complex Lung Disease. Front Microbiol. 2019,10:3081. doi: 10.3389/fmicb.2019.03081
    Read this paper
  • Lu CH, Lin ST, Chou HC, et al. Proteomic analysis of retinopathy-related plasma biomarkers in diabetic patients. Arch Biochem Biophys. 2013,529(2):146-56. doi: 10.1016/j.abb.2012.11.004
    Read this paper