VK-28

MedChem Express

VK-28 [312611-92-0]

14

312611-92-0

Research Use Only

C16H21N3O2

287.36

VK-28, a brain-permeable iron chelator, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation, with an IC50 of 12.7 microM. VK-28 exhibits significant neuroprotective effects on ICV-6-OHDA. VK-28 can be used for the research of Parkinsons disease and other neurodegenerative diseases[1].

OCCN1CCN(CC1)CC2=C3C=CC=NC3=C(C=C2)O

12352200