VL285 Phenol

MedChem Express

VL285 Phenol [1448188-69-9]

10

Research Use Only

98.56

C29H32N4O5S

548.65

VL285 Phenol is a phenol-based VL285 analog. VL285 is an E3 ubiquitin ligase VHL ligand and can be used in the synthesis of HaloPROTAC3, degrading HaloTag7 fusion protein (IC50=0.34 microM).

CC(N=CS1)=C1C2=CC(O)=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](N4CC(C=CC=C5)=C5C4=O)C(C)C)=O)=O)C=C2

-20°C,2°C to 8°C

12131703