Vodobatinib

MedChem Express

Vodobatinib [1388803-90-4]

10

1388803-90-4

Research Use Only

99.85

C27H20ClN3O2

453.92

Vodobatinib (K0706) is a potent, third generation and orally active Bcr-Abl1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants, and has no activity against BCR-ABL1T315I. Vodobatinib can be used for chronic myeloid leukemia (CML) research[1][2]. Vodobatinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(NNC(C1=CC=C(C)C(C#CC2=CC3=CC=CC=C3N=C2)=C1)=O)C4=C(C)C=CC=C4Cl

-20°C,2°C to 8°C

12352200