Vofopitant (dihydrochloride) [168266-51-1]

MedChem Express

Vofopitant (dihydrochloride) [168266-51-1]

10

168266-51-1

Research Use Only

99.56

C21H25Cl2F3N6O

505.36

Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [3H]SP binding to the NK1 receptor with pKi values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent[1].

COC1=C(CN[C@H]2CCCN[C@H]2C3=CC=CC=C3)C=C(N4N=NN=C4C(F)(F)F)C=C1.[H]Cl.[H]Cl

2°C to 8°C

12352200