Volasertib (trihydrochloride) [946161-17-7]
HY-12137A
CAS Number946161-17-7
Product group Chemicals
Molecular Weight728.20
Overview
- SupplierMedChem Express
- Product NameVolasertib (trihydrochloride) [946161-17-7]
- Delivery Days Customer10
- CAS Number946161-17-7
- CertificationResearch Use Only
- Molecular FormulaC34H53Cl3N8O3
- Molecular Weight728.20
- Scientific DescriptionVolasertib (BI 6727) trihydrochloride is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. Volasertib trihydrochloride inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib trihydrochloride induces mitotic arrest and apoptosis. Volasertib trihydrochloride, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models[1][2].
- SMILESO=C(C1=CC=C(C(OC)=C1)NC2=NC=C(N(C3=O)C)C(N([C@@H]3CC)C(C)C)=N2)N[C@H]4CC[C@@H](CC4)N5CCN(CC5)CC6CC6.[H]Cl.[H]Cl.[H]Cl
- UNSPSC12352200
MSDS
Related products
![Volasertib trihydrochloride [946161-17-7]](https://www.targetmol.com/group3/M00/02/EE/CgoaEGY7QgiEe9NhAAAAAHYWubA798.png)
Product group Chemicals
CAS Number946161-17-7
Molecular Weight728.2
- SizePrice
Product group Chemicals
Volasertib trihydrochlorideORB1690124
CAS Number946161-17-7
Estimated Purity98%
Molecular Weight728.2
- SizePrice