von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker)(IIIE2.34), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC040934
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetVWF
Overview
- SupplierBiotium
- Product Namevon Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker)(IIIE2.34), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDIIIE2.34
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID7450
- Target nameVWF
- Target descriptionvon Willebrand factor
- Target synonymscoagulation factor VIII VWF; F8VWF; von Willebrand factor; VWD
- HostMouse
- IsotypeIgG1
- Protein IDP04275
- Protein Namevon Willebrand factor
- Scientific Descriptionvon Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203