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Vonoprazan (hydrochloride) [1957202-44-6]

HY-100007A
MedChem Express
CAS Number1957202-44-6
Product group Chemicals
Molecular Weight381.85
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Vonoprazan (hydrochloride) [1957202-44-6]
  • Delivery Days Customer
    10
  • CAS Number
    1957202-44-6
  • Certification
    Research Use Only
  • Molecular Formula
    C17H17ClFN3O2S
  • Molecular Weight
    381.85
  • Scientific Description
    Vonoprazan hydrochloride, a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan hydrochloride inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan hydrochloride is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan hydrochloride can be used for eradication of Helicobacter pylori[1][2][3].
  • SMILES
    O=S(C1=CC=CN=C1)(N2C=C(CNC)C=C2C3=C(F)C=CC=C3)=O.Cl
  • UNSPSC
    12352200