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Vorinostat

HY-10221
MedChem Express
CAS Number149647-78-9
Product group Chemicals
Estimated Purity99.95
Molecular Weight264.32
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Vorinostat [149647-78-9]
  • Delivery Days Customer
    10
  • CAS Number
    149647-78-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.95
  • Molecular Formula
    C14H20N2O3
  • Molecular Weight
    264.32
  • Scientific Description
    Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1 , HDAC2 and HDAC3 (Class I) , HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV) , with ID 50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis [1] [4] . Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification [7] .
  • SMILES
    O=C(NC1=CC=CC=C1)CCCCCCC(NO)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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