Vorinostat

MedChem Express

Vorinostat [149647-78-9]

10

149647-78-9

Research Use Only

99.95

C14H20N2O3

264.32

Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1 , HDAC2 and HDAC3 (Class I) , HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV) , with ID 50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis [1] [4] . Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification [7] .

O=C(NC1=CC=CC=C1)CCCCCCC(NO)=O

-20°C,2°C to 8°C

12352200