VPC-14449 [1621375-32-3]

MedChem Express

VPC-14449 [1621375-32-3]

10

1621375-32-3

Research Use Only

99.51

C10H10Br2N4OS

394.09

VPC-14449 is a potent and selective inhibitor of the DNA-binding domain of the androgen receptor (AR-DBD), with IC50 of 0.34 microM for full-length human AR. VPC-14449 reduces the ability of full-length AR as well as AR variants to interact with chromatin. VPC-14449 can be used for the research of prostate cancer[1][2].

BrC1=CN(C2=CSC(N3CCOCC3)=N2)C(Br)=N1

-20°C,2°C to 8°C

12352200