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VPS26 antibody [C2C3], C-term

GTX106297
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetVPS26A
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Overview

  • Supplier
    GeneTex
  • Product Name
    VPS26 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.57 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9559
  • Target name
    VPS26A
  • Target description
    VPS26, retromer complex component A
  • Target synonyms
    HB58; Hbeta58; PEP8A; vacuolar protein sorting 26 homolog A; vacuolar protein sorting-associated protein 26A; vesicle protein sorting 26A; VPS26; VPS26 retromer complex comonent A
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Proteostatic modulation in brain aging without associated Alzheimers disease-and age-related neuropathological changes.
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  • Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to alpha-Synuclein Gain. Lin G et al., 2018 Oct 2, Cell Metab
    Read more