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VPS34 antibody

Name: VPS34 antibody
SKU: GTX129528_G10
Availability: BackOrder

GTX129528

ApplicationsImmunoPrecipitation, Western Blot

Product group Antibodies

TargetPIK3C3

Overview

Supplier
GeneTex
Product Name
VPS34 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoPrecipitation, Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID5289
Target name
PIK3C3
Target description
phosphatidylinositol 3-kinase catalytic subunit type 3
Target synonyms
VPS34, Vps34, hVps34, phosphatidylinositol 3-kinase catalytic subunit type 3, PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3, phosphatidylinositol 3-kinase p100 subunit, phosphoinositide-3-kinase, class 3, vacuolar protein sorting 34 homolog
Host
Rabbit
Isotype
IgG
Protein IDQ8NEB9
Protein Name
Phosphatidylinositol 3-kinase catalytic subunit type 3
Scientific Description
Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes.
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Liang YC, Chang CC, Sheu MT, et al. The Antihistamine Deptropine Induces Hepatoma Cell Death through Blocking Autophagosome-Lysosome Fusion. Cancers (Basel). 2020,12(6). doi: 10.3390/cancers12061610
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Chen CH, Hsieh TH, Lin YC, et al. Targeting Autophagy by MPT0L145, a Highly Potent PIK3C3 Inhibitor, Provides Synergistic Interaction to Targeted or Chemotherapeutic Agents in Cancer Cells. Cancers (Basel). 2019,11(9). doi: 10.3390/cancers11091345
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Chen CH, Changou CA, Hsieh TH, et al. Dual Inhibition of PIK3C3 and FGFR as a New Therapeutic Approach to Treat Bladder Cancer. Clin Cancer Res. 2018,24(5):1176-1189. doi: 10.1158/1078-0432.CCR-17-2066
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Jiang X, Bao Y, Liu H, et al. VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017,36(50):6850-6862. doi: 10.1038/onc.2017.295
Read this paper
Wakatsuki S, Tokunaga S, Shibata M, et al. GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration. J Cell Biol. 2017,216(2):477-493. doi: 10.1083/jcb.201606020
Read this paper