Vps34-IN-2 [1523404-29-6]

MedChem Express

Vps34-IN-2 [1523404-29-6]

10

1523404-29-6

Research Use Only

99.49%

C18H25F3N4O3

402.41

Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively. Vps34-IN-2 shows antiviral activity against SARS-CoV-2 (IC50 of 3.1 microM), HCoV-229E (IC50 of 0.7 microM) and HCoV-OC43.

O=C1C=C(N2[C@H](C)COCC2)N=C3N(CC(C(C)C)=O)[C@H](C(F)(F)F)CCN31

2°C to 8°C,-20°C,-80°C

12352200