VPS37A Polyclonal Antibody
RD84757A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetVPS37A
Overview
- SupplierReddot Biotech
- Product NameVPS37A Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID137492
- Target nameVPS37A
- Target descriptionVPS37A subunit of ESCRT-I
- Target synonymsESCRT-I complex subunit VPS37A; HCRP1; hepatocellular carcinoma-related protein 1; polyglutamine binding protein 2; PQBP2; SPG53; vacuolar protein sorting 37 homolog A; vacuolar protein sorting-associated protein 37A; VPS37A, ESCRT-I subunit
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203