VPS52 Antibody, FITC conjugated

Cusabio

VPS52 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

VPS52

VPS52 subunit of GARP complex

ARE1; dJ1033B10.5; SAC2; SAC2 suppressor of actin mutations 2-like protein; SACM2L; vacuolar protein sorting 52 homolog; vacuolar protein sorting-associated protein 52 homolog; VPS52, GARP complex subunit

Rabbit

IgG

Vacuolar protein sorting-associated protein 52 homolog

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).

Human

-20°C or -80°C

12352203